2/20/2023 0 Comments Types of retrospective studies6 As is well known, the treatment efficiency could be influenced by multiple factors such as age, location, skin colour, etc. 4, 5ĭespite the availability of multiple treatment options, the treatment of port-wine stains remains a worldwide problem. 3 Moreover in 16 to 50% of patients reappearance occurs after pulsed-dye laser treatment. However, complete clearance is achieved in less than 10% of patients by pulsed-dye laser. ![]() 2 To date, the pulsed-dye laser is the gold standard for the treatment of port-wine stains. 1 There are approximately 25 million patients worldwide. Port-wine stains are congenital vascular malformations with an incidence of 3- neonates. Hence a treatment plan should be scientifically selected with regards to the pathological characteristics of port-wine stains. In addition, the types of vessels changed, venous malformations gradually increased, and arteriovenous malformations and tissue hyperplasia occurred, further increasing the difficulty of treatment. ![]() As the disease progressed, vessel diameters became larger, the vessel wall became thicker and vessels were found in greater depth. The aim of our study was to characterize the histological characteristics of different types of port-wine stains. However, it is substantially related to the pathological characteristics of port-wine stains: vessel diameter, vessel depth, vessel density, vessel wall thickness and fibers in the lesions. As is well known, the treatment efficiency could be influenced by multiple factors such as age, location, skin color, etc. Port-wine stains are defined as congenital benign vascular malformations and the treatment of port-wine stains remains a challenge worldwide. A treatment plan should be scientifically formulated keeping in mind the histological characteristics of port-wine stains. ConclusionĪs the disease progresses, vessel diameters become larger, the vessel wall becomes thicker and vessels were found in a greater depth. The main limitation of the current study was the small number of patients. The vessels in red port-wine stains, purple port-wine stains and hypertrophic port-wine stains were mainly composed of capillary and venous malformations, whereas those in nodular port-wine stains were venous or arteriovenous malformations. ResultsĪ total of 35 port-wine stains patients were included in the study of four distinct types, namely red port-wine stains (11 cases), purple port-wine stains (seven cases), hypertrophic port-wine stains (nine cases) and nodular port-wine stains (eight cases). ![]() H&E staining, Immunofluorescence staining, Masson’s trichrome staining and Weigert staining were performed on the tissues. Methods and materialsīiopsies were from the hospital from 2015 to 2021. This study aimed to analyze the histological characteristics in different types of port-wine stains and provide guidance for clinical decision-making. The treatment of port-wine stains remains a challenge, worldwide. Port-wine stains are defined as congenital benign vascular lesions.
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